Transformation-associated recombination (TAR) cloning in yeast is a technique to selectively isolate a gene sequence without the construction of a genomic library. It involves the recombination between the two ‘hooks’ of the TAR vector and the flanking sequence of the targeted gene. Application of TAR cloning includes the analysis of the disease causing genome of [...]
Monoclonal antibodies (mAbs) was considered to have the potential to be the golden ‘bullet’ in human therapeutics. The term magic ‘bullet’ concept was coined by the Nobel Prize lorret and it describes that if a compound that can seek out and target a disease organism, than a toxin can be delivered. These are called conjugated [...]
Imagine a bacterium that, when injected into the bloodstream, would travel to the site of a tumor, insert itself into the cancer cell, and then produce a cancer-killing compound. That’s exactly what scientists at the University of California, Berkeley (UCB) and University of California, San Francisco (UCSF) have set out to do. Traditional cancer therapies [...]
Bacteria like Salmonella have a complicated immune system that helps them recognize and isolate foreign DNA trying to invade their cell membrane, according to a University of Washington-led study in the June 8 issue of Science Express.read more | digg story
Cipro for anthrax, Tamiflu for Avian influenza, and potassium iodine for radiation poisoning??? But how effective would this be? For example, once exposed to the bird flu you have 48hrs to take Tamiflu to be most effective. Most people would not know when they have exposed to the virus. One way to get around this [...]